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In vivo delivery of VEGF RNA and protein to increase osteogenesis and intraosseous angiogenesis
Deficient bone vasculature is a key component in pathological conditions ranging from developmental skeletal abnormalities to impaired bone repair. Vascularisation is dependent upon vascular endothelial growth factor (VEGF), which drives both angiogenesis and osteogenesis. The aim of this study was...
Autores principales: | Rumney, Robin M. H., Lanham, Stuart A., Kanczler, Janos M., Kao, Alexander P., Thiagarajan, Lalitha, Dixon, James E., Tozzi, Gianluca, Oreffo, Richard O. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882814/ https://www.ncbi.nlm.nih.gov/pubmed/31780671 http://dx.doi.org/10.1038/s41598-019-53249-4 |
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