Pharmacogenetics of amfepramone in healthy Mexican subjects reveals potential markers for tailoring pharmacotherapy of obesity: results of a randomised trial

Amfepramone (AFP) is an appetite-suppressant drug used in the treatment of obesity. Nonetheless, studies on interindividual pharmacokinetic variability and its association with genetic variants are limited. We employed a pharmacokinetic and pharmacogenetic approach to determine possible metabolic ph...

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Detalles Bibliográficos
Autores principales: Gómez-Silva, Magdalena, Piñeyro-Garza, Everardo, Vargas-Zapata, Rigoberto, Gamino-Peña, María Elena, León-García, Armando, de León, Mario Bermúdez, Llerena, Adrián, León-Cachón, Rafael B. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882847/
https://www.ncbi.nlm.nih.gov/pubmed/31780765
http://dx.doi.org/10.1038/s41598-019-54436-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882847/
https://www.ncbi.nlm.nih.gov/pubmed/31780765
http://dx.doi.org/10.1038/s41598-019-54436-z

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