Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs

Cellular uptake is limiting for the efficacy of many cytotoxic drugs used to treat cancer. Identifying endocytic mechanisms that can be modulated with targeted, clinically-relevant interventions is important to enhance the efficacy of various cancer drugs. We identify that flotillin-dependent endocy...

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Detalles Bibliográficos
Autores principales: Fekri, Farnaz, Abousawan, John, Bautista, Stephen, Orofiamma, Laura, Dayam, Roya M., Antonescu, Costin N., Karshafian, Raffi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882852/
https://www.ncbi.nlm.nih.gov/pubmed/31780775
http://dx.doi.org/10.1038/s41598-019-54062-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882852/
https://www.ncbi.nlm.nih.gov/pubmed/31780775
http://dx.doi.org/10.1038/s41598-019-54062-9

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