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Targeted enhancement of flotillin-dependent endocytosis augments cellular uptake and impact of cytotoxic drugs
Cellular uptake is limiting for the efficacy of many cytotoxic drugs used to treat cancer. Identifying endocytic mechanisms that can be modulated with targeted, clinically-relevant interventions is important to enhance the efficacy of various cancer drugs. We identify that flotillin-dependent endocy...
Autores principales: | Fekri, Farnaz, Abousawan, John, Bautista, Stephen, Orofiamma, Laura, Dayam, Roya M., Antonescu, Costin N., Karshafian, Raffi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882852/ https://www.ncbi.nlm.nih.gov/pubmed/31780775 http://dx.doi.org/10.1038/s41598-019-54062-9 |
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