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Alpha-PET for Prostate Cancer: Preclinical investigation using (149)Tb-PSMA-617

In this study, it was aimed to investigate (149)Tb-PSMA-617 for targeted α-therapy (TAT) using a mouse model of prostate-specific membrane antigen (PSMA)-expressing prostate cancer. (149)Tb-PSMA-617 was prepared with >98% radiochemical purity (6 MBq/nmol) for the treatment of mice with PSMA-posit...

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Detalles Bibliográficos
Autores principales: Umbricht, Christoph A., Köster, Ulli, Bernhardt, Peter, Gracheva, Nadezda, Johnston, Karl, Schibli, Roger, van der Meulen, Nicholas P., Müller, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882876/
https://www.ncbi.nlm.nih.gov/pubmed/31780798
http://dx.doi.org/10.1038/s41598-019-54150-w