Pharmacokinetics of Micafungin in Critically Ill Patients

We investigated covariates of pharmacokinetics of micafungin in critically ill patients. After application of micafungin, plasma samples were collected. Non-linear mixed effects modelling (NONMEM 7.3) was used to develop the pharmacokinetic model. Using this model, the adequacy of a fixed 100 mg dos...

Descripción completa

Detalles Bibliográficos
Autores principales: Gastine, Silke, Lanckohr, Christian, Blessou, Magalie, Horn, Dagmar, Fobker, Manfred, Bause, Daniela, Hempel, Georg, Ellger, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882900/
https://www.ncbi.nlm.nih.gov/pubmed/31780687
http://dx.doi.org/10.1038/s41598-019-53093-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882900/
https://www.ncbi.nlm.nih.gov/pubmed/31780687
http://dx.doi.org/10.1038/s41598-019-53093-6

Ejemplares similares