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In silico Design of an Epitope-Based Vaccine Ensemble for Chagas Disease

Trypanosoma cruzi infection causes Chagas disease, which affects 7 million people worldwide. Two drugs are available to treat it: benznidazole and nifurtimox. Although both are efficacious against the acute stage of the disease, this is usually asymptomatic and goes undiagnosed and untreated. Diagno...

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Detalles Bibliográficos
Autores principales: Michel-Todó, Lucas, Reche, Pedro Antonio, Bigey, Pascal, Pinazo, Maria-Jesus, Gascón, Joaquim, Alonso-Padilla, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882931/
https://www.ncbi.nlm.nih.gov/pubmed/31824493
http://dx.doi.org/10.3389/fimmu.2019.02698