Amplicon deep sequencing improves Plasmodium falciparum genotyping in clinical trials of antimalarial drugs

Clinical trials monitoring malaria drug resistance require genotyping of recurrent Plasmodium falciparum parasites to distinguish between treatment failure and new infection occurring during the trial follow up period. Because trial participants usually harbour multi-clonal P. falciparum infections,...

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Detalles Bibliográficos
Autores principales: Gruenberg, Maria, Lerch, Anita, Beck, Hans-Peter, Felger, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883076/
https://www.ncbi.nlm.nih.gov/pubmed/31780741
http://dx.doi.org/10.1038/s41598-019-54203-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883076/
https://www.ncbi.nlm.nih.gov/pubmed/31780741
http://dx.doi.org/10.1038/s41598-019-54203-0

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