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Amplicon deep sequencing improves Plasmodium falciparum genotyping in clinical trials of antimalarial drugs
Clinical trials monitoring malaria drug resistance require genotyping of recurrent Plasmodium falciparum parasites to distinguish between treatment failure and new infection occurring during the trial follow up period. Because trial participants usually harbour multi-clonal P. falciparum infections,...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883076/ https://www.ncbi.nlm.nih.gov/pubmed/31780741 http://dx.doi.org/10.1038/s41598-019-54203-0 |