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Long-term monitoring in a microfluidic system to study tumour spheroid response to chronic and cycling hypoxia
We demonstrate the application of a microfluidic platform combining spatiotemporal oxygen control and long-term microscopy monitoring to observe tumour spheroid response to hypoxia. The platform is capable of recreating physiologically-relevant low and cycling oxygen levels not attainable in traditi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883080/ https://www.ncbi.nlm.nih.gov/pubmed/31780697 http://dx.doi.org/10.1038/s41598-019-54001-8 |