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Long-term monitoring in a microfluidic system to study tumour spheroid response to chronic and cycling hypoxia

We demonstrate the application of a microfluidic platform combining spatiotemporal oxygen control and long-term microscopy monitoring to observe tumour spheroid response to hypoxia. The platform is capable of recreating physiologically-relevant low and cycling oxygen levels not attainable in traditi...

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Detalles Bibliográficos
Autores principales: Grist, Samantha M., Nasseri, S. Soroush, Laplatine, Loïc, Schmok, Jonathan C., Yao, Dickson, Hua, Jessica, Chrostowski, Lukas, Cheung, Karen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883080/
https://www.ncbi.nlm.nih.gov/pubmed/31780697
http://dx.doi.org/10.1038/s41598-019-54001-8