Syk‐dependent glycolytic reprogramming in dendritic cells regulates IL‐1β production to β‐glucan ligands in a TLR‐independent manner

Dendritic cells (DCs) activated via TLR ligation experience metabolic reprogramming, in which the cells are heavily dependent on glucose and glycolysis for the synthesis of molecular building blocks essential for maturation, cytokine production, and the ability to stimulate T cells. Although the TLR...

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Detalles Bibliográficos
Autores principales: Thwe, Phyu M., Fritz, Daniel I., Snyder, Julia P., Smith, Portia R., Curtis, Kylie D., O'Donnell, Alexandra, Galasso, Nicholas A., Sepaniac, Leslie A., Adamik, Benjamin J., Hoyt, Laura R., Rodriguez, Princess D., Hogan, Tyler C., Schmidt, Andrea F., Poynter, Matthew E., Amiel, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Inflammation, Extracellular Mediators, & Effector Molecules
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883127/
https://www.ncbi.nlm.nih.gov/pubmed/31509298
http://dx.doi.org/10.1002/JLB.3A0819-207RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883127/
https://www.ncbi.nlm.nih.gov/pubmed/31509298
http://dx.doi.org/10.1002/JLB.3A0819-207RR

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