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Loss of Tiparp Results in Aberrant Layering of the Cerebral Cortex

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly-ADP-ribose polymerase (TIPARP) is an enzyme that adds a single ADP-ribose moiety to itself or other proteins. Tiparp is highly expressed in the brain; however, its function in this organ is unknown. Here, we used Tiparp(–/–) mice to determine...

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Detalles Bibliográficos
Autores principales: Grimaldi, Giulia, Vagaska, Barbora, Ievglevskyi, Oleksandr, Kondratskaya, Elena, Glover, Joel C., Matthews, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883171/
https://www.ncbi.nlm.nih.gov/pubmed/31704703
http://dx.doi.org/10.1523/ENEURO.0239-19.2019