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Testing Mediation Effects in High-Dimensional Epigenetic Studies

Mediation analysis has been a powerful tool to identify factors mediating the association between exposure variables and outcomes. It has been applied to various genomic applications with the hope to gain novel insights into the underlying mechanism of various diseases. Given the high-dimensional na...

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Detalles Bibliográficos
Autores principales: Gao, Yuzhao, Yang, Haitao, Fang, Ruiling, Zhang, Yanbo, Goode, Ellen L., Cui, Yuehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883258/
https://www.ncbi.nlm.nih.gov/pubmed/31824577
http://dx.doi.org/10.3389/fgene.2019.01195