Acute liver failure in a military recruit treated with valproic acid and harboring a previously unrecognized POLG-1 mutation

Patients with mutations in the POLG-1 gene often are afflicted with drug-resistant seizures at an early age and have an increased risk of valproic acid-induced acute liver failure. Severe valproate hepatotoxicity most commonly arises in children within the first 3 months of treatment with an overall...

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Detalles Bibliográficos
Autores principales: Bassett, John T., Rodriguez, Benjamin, Mulligan, Lisa, Fontana, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883298/
https://www.ncbi.nlm.nih.gov/pubmed/31799506
http://dx.doi.org/10.1016/j.ebr.2019.100342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883298/
https://www.ncbi.nlm.nih.gov/pubmed/31799506
http://dx.doi.org/10.1016/j.ebr.2019.100342

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