Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms

Glutathione peroxidase 2 (GPx2) is one of the five selenoprotein GPxs having a selenocysteine in the active center. GPx2 is strongly expressed in the gastrointestinal epithelium, as is another isoform, GPx1, though with a different localization pattern. Both GPxs are redox-active enzymes that are im...

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Detalles Bibliográficos
Autores principales: Koeberle, Solveigh C., Gollowitzer, André, Laoukili, Jamila, Kranenburg, Onno, Werz, Oliver, Koeberle, Andreas, Kipp, Anna P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883322/
https://www.ncbi.nlm.nih.gov/pubmed/31765890
http://dx.doi.org/10.1016/j.redox.2019.101388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883322/
https://www.ncbi.nlm.nih.gov/pubmed/31765890
http://dx.doi.org/10.1016/j.redox.2019.101388

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