Cargando…
Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms
Glutathione peroxidase 2 (GPx2) is one of the five selenoprotein GPxs having a selenocysteine in the active center. GPx2 is strongly expressed in the gastrointestinal epithelium, as is another isoform, GPx1, though with a different localization pattern. Both GPxs are redox-active enzymes that are im...
Autores principales: | Koeberle, Solveigh C., Gollowitzer, André, Laoukili, Jamila, Kranenburg, Onno, Werz, Oliver, Koeberle, Andreas, Kipp, Anna P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883322/ https://www.ncbi.nlm.nih.gov/pubmed/31765890 http://dx.doi.org/10.1016/j.redox.2019.101388 |
Ejemplares similares
-
The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages
por: Wolfram, Theresa, et al.
Publicado: (2021) -
Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides
por: Schwarz, Maria, et al.
Publicado: (2023) -
α-Tocopherol-13′-Carboxychromanol Induces Cell Cycle Arrest and Cell Death by Inhibiting the SREBP1-SCD1 Axis and Causing Imbalance in Lipid Desaturation
por: Liao, Sijia, et al.
Publicado: (2023) -
The contribution of glutathione peroxidases to chloroplast redox homeostasis in Arabidopsis
por: Casatejada, Azahara, et al.
Publicado: (2023) -
Developmental stage-dependent regulation of spine formation by calcium-calmodulin-dependent protein kinase IIα and Rap1
por: Cornelia Koeberle, Solveigh, et al.
Publicado: (2017)