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Metabolic reprogramming of Salmonella infected macrophages and its modulation by iron availability and the mTOR pathway

Iron is an essential nutrient for immune cells and microbes, therefore the control of its homeostasis plays a decisive role for infections. Moreover, iron affects metabolic pathways by modulating the translational expression of the key tricarboxylic acid cycle (TCA) enzyme mitochondrial aconitase an...

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Detalles Bibliográficos
Autores principales: Telser, Julia, Volani, Chiara, Hilbe, Richard, Seifert, Markus, Brigo, Natascha, Paglia, Giuseppe, Weiss, Günter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883347/
https://www.ncbi.nlm.nih.gov/pubmed/31832425
http://dx.doi.org/10.15698/mic2019.12.700