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Mineralocorticoid Receptor-Dependent Impairment of Baroreflex Contributes to Hypertension in a Mouse Model of Primary Aldosteronism

Primary aldosteronism (PA) is the most common cause of secondary hypertension. The paucity of good animal models hinders our understanding of the pathophysiology of PA and the hypertensive mechanism of PA remains incompletely known. It was recently reported that genetic deletion of TWIK-related acid...

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Detalles Bibliográficos
Autores principales: Shi, Luo, Yuan, Fang, Wang, Xuefang, Wang, Ri, Liu, Kun, Tian, Yanming, Guo, Zan, Zhang, Xiangjian, Wang, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883352/
https://www.ncbi.nlm.nih.gov/pubmed/31824340
http://dx.doi.org/10.3389/fphys.2019.01434