Common DNA sequence variation influences 3-dimensional conformation of the human genome

BACKGROUND: The 3-dimensional (3D) conformation of chromatin inside the nucleus is integral to a variety of nuclear processes including transcriptional regulation, DNA replication, and DNA damage repair. Aberrations in 3D chromatin conformation have been implicated in developmental abnormalities and...

Descripción completa

Detalles Bibliográficos
Autores principales: Gorkin, David U., Qiu, Yunjiang, Hu, Ming, Fletez-Brant, Kipper, Liu, Tristin, Schmitt, Anthony D., Noor, Amina, Chiou, Joshua, Gaulton, Kyle J., Sebat, Jonathan, Li, Yun, Hansen, Kasper D., Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883528/
https://www.ncbi.nlm.nih.gov/pubmed/31779666
http://dx.doi.org/10.1186/s13059-019-1855-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883528/
https://www.ncbi.nlm.nih.gov/pubmed/31779666
http://dx.doi.org/10.1186/s13059-019-1855-4

Ejemplares similares