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Colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia (Magic Bullet study): an investigator-driven, open-label, randomized, noninferiority controlled trial

BACKGROUND: Colistin is recommended in the empirical treatment of ventilator-associated pneumonia (VAP) with a high prevalence of carbapenem-resistant gram-negative bacilli (CR-GNB). However, the efficacy and safety of colistin are not well defined. METHODS: A multicenter prospective randomized tria...

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Detalles Bibliográficos
Autores principales: Cisneros, José M., Rosso-Fernández, Clara María, Roca-Oporto, Cristina, De Pascale, Gennaro, Jiménez-Jorge, Silvia, Fernández-Hinojosa, Esteban, Matthaiou, Dimitrios K., Ramírez, Paula, Díaz-Miguel, Ramón Ortiz, Estella, Angel, Antonelli, Massimo, Dimopoulos, George, Garnacho-Montero, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883535/
https://www.ncbi.nlm.nih.gov/pubmed/31779711
http://dx.doi.org/10.1186/s13054-019-2627-y