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Colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia (Magic Bullet study): an investigator-driven, open-label, randomized, noninferiority controlled trial
BACKGROUND: Colistin is recommended in the empirical treatment of ventilator-associated pneumonia (VAP) with a high prevalence of carbapenem-resistant gram-negative bacilli (CR-GNB). However, the efficacy and safety of colistin are not well defined. METHODS: A multicenter prospective randomized tria...
Autores principales: | Cisneros, José M., Rosso-Fernández, Clara María, Roca-Oporto, Cristina, De Pascale, Gennaro, Jiménez-Jorge, Silvia, Fernández-Hinojosa, Esteban, Matthaiou, Dimitrios K., Ramírez, Paula, Díaz-Miguel, Ramón Ortiz, Estella, Angel, Antonelli, Massimo, Dimopoulos, George, Garnacho-Montero, José |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883535/ https://www.ncbi.nlm.nih.gov/pubmed/31779711 http://dx.doi.org/10.1186/s13054-019-2627-y |
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