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Long non-coding RNA MALAT1 enhances the apoptosis of cardiomyocytes through autophagy inhibition by regulating TSC2-mTOR signaling

BACKGROUND: Our previous study showed that knockdown of long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) attenuated myocardial apoptosis in mouse acute myocardial infarction (AMI). This study aims to explore whether MALAT1 enhanced cardiomyocyte apoptosis v...

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Detalles Bibliográficos
Autores principales: Hu, Hao, Wu, Jiawei, Yu, Xiaofan, Zhou, Junling, Yu, Hua, Ma, Likun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883637/
https://www.ncbi.nlm.nih.gov/pubmed/31783925
http://dx.doi.org/10.1186/s40659-019-0265-0