Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition

Ebola virus high lethality relies on its ability to efficiently bypass the host innate antiviral response, which senses the viral dsRNA through the RIG-I receptor and induces type I interferon α/β production. In the bypassing action, the Ebola virus protein VP35 plays a pivotal role at multiple leve...

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Detalles Bibliográficos
Autores principales: Di Palma, Francesco, Daino, Gian Luca, Ramaswamy, Venkata Krishnan, Corona, Angela, Frau, Aldo, Fanunza, Elisa, Vargiu, Attilio V, Tramontano, Enzo, Ruggerone, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883671/
https://www.ncbi.nlm.nih.gov/pubmed/31744306
http://dx.doi.org/10.1177/2040206619889220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883671/
https://www.ncbi.nlm.nih.gov/pubmed/31744306
http://dx.doi.org/10.1177/2040206619889220

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