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Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy
BACKGROUND: Sepsis-associated encephalopathy (SAE), a diffuse cerebral dysfunction in the absence of direct CNS infection, is associated with increased rates of mortality and morbidity in patients with sepsis. Increased cytokine production and disruption of the blood-brain barrier (BBB) are implicat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883676/ https://www.ncbi.nlm.nih.gov/pubmed/31779628 http://dx.doi.org/10.1186/s12974-019-1575-4 |