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Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy

BACKGROUND: Sepsis-associated encephalopathy (SAE), a diffuse cerebral dysfunction in the absence of direct CNS infection, is associated with increased rates of mortality and morbidity in patients with sepsis. Increased cytokine production and disruption of the blood-brain barrier (BBB) are implicat...

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Detalles Bibliográficos
Autores principales: Kikuchi, Daniel S., Campos, Ana Carolina P., Qu, Hongyan, Forrester, Steven J., Pagano, Rosana L., Lassègue, Bernard, Sadikot, Ruxana T., Griendling, Kathy K., Hernandes, Marina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883676/
https://www.ncbi.nlm.nih.gov/pubmed/31779628
http://dx.doi.org/10.1186/s12974-019-1575-4