methylCC: technology-independent estimation of cell type composition using differentially methylated regions

A major challenge in the analysis of DNA methylation (DNAm) data is variability introduced from intra-sample cellular heterogeneity, such as whole blood which is a convolution of DNAm profiles across a unique cell type. When this source of variability is confounded with an outcome of interest, if un...

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Detalles Bibliográficos
Autores principales: Hicks, Stephanie C., Irizarry, Rafael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883691/
https://www.ncbi.nlm.nih.gov/pubmed/31783894
http://dx.doi.org/10.1186/s13059-019-1827-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883691/
https://www.ncbi.nlm.nih.gov/pubmed/31783894
http://dx.doi.org/10.1186/s13059-019-1827-8

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