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methylCC: technology-independent estimation of cell type composition using differentially methylated regions

A major challenge in the analysis of DNA methylation (DNAm) data is variability introduced from intra-sample cellular heterogeneity, such as whole blood which is a convolution of DNAm profiles across a unique cell type. When this source of variability is confounded with an outcome of interest, if un...

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Detalles Bibliográficos
Autores principales:	Hicks, Stephanie C., Irizarry, Rafael A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883691/ https://www.ncbi.nlm.nih.gov/pubmed/31783894 http://dx.doi.org/10.1186/s13059-019-1827-8

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