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Characterizing the interplay between gene nucleotide composition bias and splicing

BACKGROUND: Nucleotide composition bias plays an important role in the 1D and 3D organization of the human genome. Here, we investigate the potential interplay between nucleotide composition bias and the regulation of exon recognition during splicing. RESULTS: By analyzing dozens of RNA-seq datasets...

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Detalles Bibliográficos
Autores principales: Lemaire, Sébastien, Fontrodona, Nicolas, Aubé, Fabien, Claude, Jean-Baptiste, Polvèche, Hélène, Modolo, Laurent, Bourgeois, Cyril F., Mortreux, Franck, Auboeuf, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883713/
https://www.ncbi.nlm.nih.gov/pubmed/31783898
http://dx.doi.org/10.1186/s13059-019-1869-y