Intrinsic elasticity of nucleosomes is encoded by histone variants and calibrated by their binding partners

Histone variants fine-tune transcription, replication, DNA damage repair, and faithful chromosome segregation. Whether and how nucleosome variants encode unique mechanical properties to their cognate chromatin structures remains elusive. Here, using in silico and in vitro nanoindentation methods, ex...

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Detalles Bibliográficos
Autores principales: Melters, Daniël P., Pitman, Mary, Rakshit, Tatini, Dimitriadis, Emilios K., Bui, Minh, Papoian, Garegin A., Dalal, Yamini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883791/
https://www.ncbi.nlm.nih.gov/pubmed/31712435
http://dx.doi.org/10.1073/pnas.1911880116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883791/
https://www.ncbi.nlm.nih.gov/pubmed/31712435
http://dx.doi.org/10.1073/pnas.1911880116

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