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Neutrophils promote VLA-4–dependent B cell antigen presentation and accumulation within the meninges during neuroinflammation
The success of B cell depletion therapies and identification of leptomeningeal ectopic lymphoid tissue (ELT) in patients with multiple sclerosis (MS) has renewed interest in the antibody-independent pathogenic functions of B cells during neuroinflammation. The timing and location of B cell antigen p...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883802/ https://www.ncbi.nlm.nih.gov/pubmed/31699814 http://dx.doi.org/10.1073/pnas.1909098116 |