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Definitive demonstration by synthesis of genome annotation completeness

We develop a method for completing the genetics of natural living systems by which the absence of expected future discoveries can be established. We demonstrate the method using bacteriophage øX174, the first DNA genome to be sequenced. Like many well-studied natural organisms, closely related genom...

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Detalles Bibliográficos
Autores principales: Jaschke, Paul R., Dotson, Gabrielle A., Hung, Kay S., Liu, Diane, Endy, Drew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883844/
https://www.ncbi.nlm.nih.gov/pubmed/31719208
http://dx.doi.org/10.1073/pnas.1905990116