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Metabolomic Assessment Reveals Alteration in Polyols and Branched Chain Amino Acids Associated With Present and Future Renal Impairment in a Discovery Cohort of 637 Persons With Type 1 Diabetes

Background: Improved understanding of the pathophysiology causing diabetic kidney disease (DKD) is imperative. The aim of this study was to uncover associations between serum metabolites and renal outcomes. Methods: Non-targeted serum metabolomics analyses were performed in samples from 637 persons...

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Detalles Bibliográficos
Autores principales: Tofte, Nete, Suvitaival, Tommi, Trost, Kajetan, Mattila, Ismo Matias, Theilade, Simone, Winther, Signe Abitz, Ahluwalia, Tarunveer Singh, Frimodt-Møller, Marie, Legido-Quigley, Cristina, Rossing, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883958/
https://www.ncbi.nlm.nih.gov/pubmed/31824430
http://dx.doi.org/10.3389/fendo.2019.00818