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TLR-2 and MyD88-Dependent Activation of MAPK and STAT Proteins Regulates Proinflammatory Cytokine Response and Immunity to Experimental Trypanosoma congolense Infection

It is known that Trypanosoma congolense infection in mice is associated with increased production of proinflammatory cytokines by macrophages and monocytes. However, the intracellular signaling pathways leading to the production of these cytokines still remain unknown. In this paper, we have investi...

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Detalles Bibliográficos
Autores principales: Kuriakose, Shiby, Onyilagha, Chukwunonso, Singh, Rani, Olayinka-Adefemi, Folayemi, Jia, Ping, Uzonna, Jude E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883972/
https://www.ncbi.nlm.nih.gov/pubmed/31824484
http://dx.doi.org/10.3389/fimmu.2019.02673