Dephosphorylation of p53 Ser 392 Enhances Trimethylation of Histone H3 Lys 9 via SUV39h1 Stabilization in CK2 Downregulation-Mediated Senescence

Cellular senescence is an irreversible form of cell cycle arrest. Senescent cells have a unique gene expression profile that is frequently accompanied by senescence-associated heterochromatic foci (SAHFs). Protein kinase CK2 (CK2) downregulation can induce trimethylation of histone H3 Lys 9 (H3K9me3...

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Detalles Bibliográficos
Autores principales: Park, Jeong-Woo, Bae, Young-Seuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883974/
https://www.ncbi.nlm.nih.gov/pubmed/31617338
http://dx.doi.org/10.14348/molcells.2019.0018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883974/
https://www.ncbi.nlm.nih.gov/pubmed/31617338
http://dx.doi.org/10.14348/molcells.2019.0018

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