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Development of a Reporter System Monitoring Regulated Intramembrane Proteolysis of the Transmembrane bZIP Transcription Factor ATF6α

When endoplasmic reticulum (ER) functions are perturbed, the ER induces several signaling pathways called unfolded protein response to reestablish ER homeostasis through three ER transmembrane proteins: inositol-requiring enzyme 1 (IRE1), PKR-like ER kinase (PERK), and activating transcription facto...

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Detalles Bibliográficos
Autores principales: Kim, Jin-Ik, Kaufman, Randal J., Back, Sung Hoon, Moon, Ja-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883980/
https://www.ncbi.nlm.nih.gov/pubmed/31707777
http://dx.doi.org/10.14348/molcells.2019.0104