Efa6 protects axons and regulates their growth and branching by inhibiting microtubule polymerisation at the cortex

Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They play important roles in neurons, as suggested by inhibition of axon growth and regeneration through the ARF activator Efa6 in C. elegans, and by neurodevelopmental disorders linked to the mammalian kinesin Kif21A...

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Detalles Bibliográficos
Autores principales: Qu, Yue, Hahn, Ines, Lees, Meredith, Parkin, Jill, Voelzmann, André, Dorey, Karel, Rathbone, Alex, Friel, Claire T, Allan, Victoria J, Okenve-Ramos, Pilar, Sanchez-Soriano, Natalia, Prokop, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884004/
https://www.ncbi.nlm.nih.gov/pubmed/31718774
http://dx.doi.org/10.7554/eLife.50319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884004/
https://www.ncbi.nlm.nih.gov/pubmed/31718774
http://dx.doi.org/10.7554/eLife.50319

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