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Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution

It is widely held that the first two blastomeres of mammalian embryos are equally totipotent and that this totipotency belongs to the group of regulative properties. However, this interpretation neglects an important aspect: evidence only came from successful monozygotic twins which can speak only f...

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Detalles Bibliográficos
Autores principales: Casser, E, Wdowik, S, Israel, S, Witten, A, Schlatt, S, Nordhoff, V, Boiani, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884417/
https://www.ncbi.nlm.nih.gov/pubmed/31504820
http://dx.doi.org/10.1093/molehr/gaz051