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A SUMO-dependent pathway controls elongating RNA Polymerase II upon UV-induced damage
RNA polymerase II (RNAPII) is the workhorse of eukaryotic transcription and produces messenger RNAs and small nuclear RNAs. Stalling of RNAPII caused by transcription obstacles such as DNA damage threatens functional gene expression and is linked to transcription-coupled DNA repair. To restore trans...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884465/ https://www.ncbi.nlm.nih.gov/pubmed/31784551 http://dx.doi.org/10.1038/s41598-019-54027-y |