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A SUMO-dependent pathway controls elongating RNA Polymerase II upon UV-induced damage

RNA polymerase II (RNAPII) is the workhorse of eukaryotic transcription and produces messenger RNAs and small nuclear RNAs. Stalling of RNAPII caused by transcription obstacles such as DNA damage threatens functional gene expression and is linked to transcription-coupled DNA repair. To restore trans...

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Detalles Bibliográficos
Autores principales:	Heckmann, Irina, Kern, Maximilian J., Pfander, Boris, Jentsch, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884465/ https://www.ncbi.nlm.nih.gov/pubmed/31784551 http://dx.doi.org/10.1038/s41598-019-54027-y

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