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Centromere 17 copy number gain reflects chromosomal instability in breast cancer

Chromosomal instability (CIN) is known to be associated with prognosis and treatment response in breast cancer. This study was conducted to determine whether copy number gain of centromere 17 (CEP17) reflects CIN, and to evaluate the prognostic and predictive value of CIN in breast cancer. CIN statu...

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Detalles Bibliográficos
Autores principales: Lee, Kyoungyul, Kim, Hyun Jeong, Jang, Min Hye, Lee, Sejoon, Ahn, Soomin, Park, So Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884473/
https://www.ncbi.nlm.nih.gov/pubmed/31784614
http://dx.doi.org/10.1038/s41598-019-54471-w