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Altered generation of ciliated cells in chronic obstructive pulmonary disease

In COPD, epithelial changes are prominent features in the airways, such as goblet cell hyperplasia and squamous metaplasia. In contrast, it remains unclear whether ciliated cells are reduced and which pathways dysregulate epithelial differentiation. We hypothesized that bronchial epithelial cell lin...

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Detalles Bibliográficos
Autores principales: Gohy, Sophie, Carlier, François M., Fregimilicka, Chantal, Detry, Bruno, Lecocq, Marylène, Ladjemi, Maha Zohra, Verleden, Stijn, Hoton, Delphine, Weynand, Birgit, Bouzin, Caroline, Pilette, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884487/
https://www.ncbi.nlm.nih.gov/pubmed/31784664
http://dx.doi.org/10.1038/s41598-019-54292-x