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The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data

We recently introduced the Gini coefficient (GC) for assessing the expression variation of a particular gene in a dataset, as a means of selecting improved reference genes over the cohort (‘housekeeping genes’) typically used for normalisation in expression profiling studies. Those genes (transcript...

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Detalles Bibliográficos
Autores principales: Wright Muelas, Marina, Mughal, Farah, O’Hagan, Steve, Day, Philip J., Kell, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884504/
https://www.ncbi.nlm.nih.gov/pubmed/31784565
http://dx.doi.org/10.1038/s41598-019-54288-7