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The role and robustness of the Gini coefficient as an unbiased tool for the selection of Gini genes for normalising expression profiling data
We recently introduced the Gini coefficient (GC) for assessing the expression variation of a particular gene in a dataset, as a means of selecting improved reference genes over the cohort (‘housekeeping genes’) typically used for normalisation in expression profiling studies. Those genes (transcript...
Autores principales: | Wright Muelas, Marina, Mughal, Farah, O’Hagan, Steve, Day, Philip J., Kell, Douglas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884504/ https://www.ncbi.nlm.nih.gov/pubmed/31784565 http://dx.doi.org/10.1038/s41598-019-54288-7 |
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