Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression

Base excision repair (BER) initiated by alkyladenine DNA glycosylase (AAG) is essential for removal of aberrantly methylated DNA bases. Genome instability and accumulation of aberrant bases accompany multiple diseases, including cancer and neurological disorders. While BER is well studied on naked D...

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Detalles Bibliográficos
Autores principales: Montaldo, Nicola P., Bordin, Diana L., Brambilla, Alessandro, Rösinger, Marcel, Fordyce Martin, Sarah L., Bjørås, Karine Øian, Bradamante, Stefano, Aas, Per Arne, Furrer, Antonia, Olsen, Lene C., Kunath, Nicolas, Otterlei, Marit, Sætrom, Pål, Bjørås, Magnar, Samson, Leona D., van Loon, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884549/
https://www.ncbi.nlm.nih.gov/pubmed/31784530
http://dx.doi.org/10.1038/s41467-019-13394-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884549/
https://www.ncbi.nlm.nih.gov/pubmed/31784530
http://dx.doi.org/10.1038/s41467-019-13394-w

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