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Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor

Interstitial chemotherapy plays a pivotal role in the treatment of glioblastoma multiforme (GBM), an aggressive form of primary brain cancer, by enhancing drug biodistribution to the tumor and avoiding systemic toxicities. The use of new polymer structures that extend the release of cytotoxic agents...

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Detalles Bibliográficos
Autores principales: Han, Daewoo, Serra, Riccardo, Gorelick, Noah, Fatima, Umailla, Eberhart, Charles G., Brem, Henry, Tyler, Betty, Steckl, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884550/
https://www.ncbi.nlm.nih.gov/pubmed/31784666
http://dx.doi.org/10.1038/s41598-019-54283-y