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Multi-layered core-sheath fiber membranes for controlled drug release in the local treatment of brain tumor
Interstitial chemotherapy plays a pivotal role in the treatment of glioblastoma multiforme (GBM), an aggressive form of primary brain cancer, by enhancing drug biodistribution to the tumor and avoiding systemic toxicities. The use of new polymer structures that extend the release of cytotoxic agents...
Autores principales: | Han, Daewoo, Serra, Riccardo, Gorelick, Noah, Fatima, Umailla, Eberhart, Charles G., Brem, Henry, Tyler, Betty, Steckl, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884550/ https://www.ncbi.nlm.nih.gov/pubmed/31784666 http://dx.doi.org/10.1038/s41598-019-54283-y |
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