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Suppression of FOXM1 activities and breast cancer growth in vitro and in vivo by a new class of compounds
The transcription factor FOXM1 is upregulated and overexpressed in aggressive, therapy-resistant forms of hormone receptor-positive and triple negative breast cancers, and is associated with less good patient survival. FOXM1 signaling is also a key driver in many other cancers. Here, we identify a n...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884575/ https://www.ncbi.nlm.nih.gov/pubmed/31815181 http://dx.doi.org/10.1038/s41523-019-0141-7 |