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Development of an ex vivo preclinical respiratory model of idiopathic pulmonary fibrosis for aerosol regional studies

Idiopathic pulmonary fibrosis is a progressive disease with unsatisfactory systemic treatments. Aerosol drug delivery to the lungs is expected to be an interesting route of administration. However, due to the alterations of lung compliance caused by fibrosis, local delivery remains challenging. This...

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Detalles Bibliográficos
Autores principales: Montigaud, Yoann, Périnel-Ragey, Sophie, Plantier, Laurent, Leclerc, Lara, Goy, Clémence, Clotagatide, Anthony, Prévôt, Nathalie, Pourchez, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884587/
https://www.ncbi.nlm.nih.gov/pubmed/31784683
http://dx.doi.org/10.1038/s41598-019-54479-2