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Development of an ex vivo preclinical respiratory model of idiopathic pulmonary fibrosis for aerosol regional studies
Idiopathic pulmonary fibrosis is a progressive disease with unsatisfactory systemic treatments. Aerosol drug delivery to the lungs is expected to be an interesting route of administration. However, due to the alterations of lung compliance caused by fibrosis, local delivery remains challenging. This...
Autores principales: | Montigaud, Yoann, Périnel-Ragey, Sophie, Plantier, Laurent, Leclerc, Lara, Goy, Clémence, Clotagatide, Anthony, Prévôt, Nathalie, Pourchez, Jérémie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884587/ https://www.ncbi.nlm.nih.gov/pubmed/31784683 http://dx.doi.org/10.1038/s41598-019-54479-2 |
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