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Enrichment of persisters enabled by a ß-lactam-induced filamentation method reveals their stochastic single-cell awakening

When exposed to lethal doses of antibiotics, bacterial populations are most often not completely eradicated. A small number of phenotypic variants, defined as ‘persisters’, are refractory to antibiotics and survive treatment. Despite their involvement in relapsing infections, processes determining p...

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Detalles Bibliográficos
Autores principales: Windels, Etthel M., Ben Meriem, Zacchari, Zahir, Taiyeb, Verstrepen, Kevin J., Hersen, Pascal, Van den Bergh, Bram, Michiels, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884588/
https://www.ncbi.nlm.nih.gov/pubmed/31815194
http://dx.doi.org/10.1038/s42003-019-0672-3