Whole blood RNA signatures in leprosy patients identify reversal reactions before clinical onset: a prospective, multicenter study

Early diagnosis of leprosy is challenging, particularly its inflammatory reactions, the major cause of irreversible neuropathy in leprosy. Current diagnostics cannot identify which patients are at risk of developing reactions. This study assessed blood RNA expression levels as potential biomarkers f...

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Detalles Bibliográficos
Autores principales: Tió-Coma, Maria, van Hooij, Anouk, Bobosha, Kidist, van der Ploeg-van Schip, Jolien J., Banu, Sayera, Khadge, Saraswoti, Thapa, Pratibha, Kunwar, Chhatra B., Goulart, Isabela M., Bekele, Yonas, Hagge, Deanna A., Moraes, Milton O., Teles, Rosane M. B., Pinheiro, Roberta Olmo, van Zwet, Erik W., Goeman, Jelle J., Aseffa, Abraham, Haks, Mariëlle C., Ottenhoff, Tom H. M., Modlin, Robert L., Geluk, Annemieke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884598/
https://www.ncbi.nlm.nih.gov/pubmed/31784594
http://dx.doi.org/10.1038/s41598-019-54213-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884598/
https://www.ncbi.nlm.nih.gov/pubmed/31784594
http://dx.doi.org/10.1038/s41598-019-54213-y

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